Contents:

• Mission Statement
• Technology Development
• Core applications to protein structure determination

The overall goals of the Resource are to develop new technology for NMR spectroscopy and to make it available to the biomedical research community for structure determination of proteins in biological supramolecular assemblies, such as membrane proteins or virus particles.

The long-term objective of the Resource is to develop and apply NMR spectroscopy so that the structures and dynamics of all expressed proteins can be described with atomic resolution without regard for the physical properties of the polypeptides, such as solubility or aggregation state. This will enable the proteins to be selected based on the interest in their biological properties and relevance to biomedical research, or in genuinely unbiased surveys of proteomes.

Structure of the Coat Protein in fd Filamentous Bacteriophage Particles

 

Contents:

• Mission Statement
• Technology Development
• Core applications to protein structure determination