Contact Information:

Education:

Ph.D. in Biochemistry (2005)
Kansas State University, Manhattan, KS

M.S. in Biochemistry (2003)
Kansas State University, Manhattan, KS

B.S. in Biology (2000)
Concordia University, Seward, NE

Publications:

Cook, G.A., Opella, (2010) Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by nmr spectroscopy. Biochim Biophys Acta. In Press.

Cook, G.A., Zhang, H., Park, S.H., Wang, Y., Opella, S.J. (2010) Comparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1. Biochim Biophys Acta. In Press. (invited review)

Cook, G.A., Stefer, S., Opella, S.J., (2010) Expression and Purification of the Membrane Protein p7 from HCV. Peptide Science. In press.

Cook, G.A., Opella, S.J. (2010) NMR studies of membrane proteins, in Membrane Transporters in Drug Discovery and Development, Methods in Molecular Biology (Yan, Q., Ed), Springer, New York, pp. 263-275 (invited book chapter)

Cook, G.A., Opella, S.J. (2009) NMR studies of p7 protein from hepatitis C virus. Eur. Biophys J. 39:1097-104 (invited review)

Wu, C.H., Grant, C.V., Cook G.A., Park S.H., Opella S.J. (2009) A strip-shield improves the efficiency of a solenoid coil in probes for high-field solid-state NMR of lossy biological samples. J. Magn. Reson. 200:74-80

Cook, G.A., Pajewski, R., Aburi, M., Smith, P.E., Prakash, O., Tomich, J.M., Gokel, G. (2006) NMR Structure and Dynamics Studies of an Anion Binding Channel-Forming Heptapeptide. J. Am. Chem. Soc. 128: 1633-1638.

Johnston, J.M., Cook, G.A., Samson, M.S., Tomich, J.M. (2006) Conformation and Environment of Channel-Forming Peptides: A Simulation Study. Biophys. J. 90: 1855-1864

Shank, L.P., Broughman, J.R., , Takeguchi, W., Cook, G.A., , Robbins, A.S., Hahn, L., Radke, G., Iwamoto, T., Schultz, B.D. and Tomich, J.M. (2006) Redesigning Channel-Forming Peptides: Amino Acid Substitutions that Enhance Rates of Supramolecular Self-Assembly and Raise Ion Transport Activity. Biophys. J. 90:2138-2150

Cook, G.A., (2005) Structural Studies of Anion Channel Forming Peptides. Doctoral Dissertation.

Cook, G.A., Prakash, O., Zhang, K., Shank, L.P., Takeguchi, W.A., Robbins, A., Gong, Y.X., Iwamoto, T., Schultz, B.D., Tomich, J.M. (2004) Activity and Structural Comparisons of Solution Associating and Monomeric Channel- Forming Peptides Derived from the Glycine Receptor M2 Segment. Biophy. J. 74:1424-1435

Cook, G.A., (2003) Structural Determination of a Monomeric Channel-Forming Peptide Derived from the Glycine Receptor M2 Segment. Master's Thesis.