Contact Information:
Department of Chemistry and Biochemistry
University of California, San Diego
Natural Sciences Building 3117
9500 Gilman Drive, 0127
La Jolla, California 92093-1027

TEL: (858) 822-4621
FAX: (858) 822-4821
email: schowell@chem.ucsd.edu

Education:
Department of Chemistry and Biochemistry (2003-present)
University of California, San Diego, CA
Advisor: Dr. Stanley J. Opella

Department of Chemistry (2001-2)
Washington State University, Pullman, WA
Advisor: Dr. Jeremy N.S. Evans

Bachelor of Science, Department of Chemistry (2001)
University of North Carolina, Asheville, NC
Advisors: Drs. Keith Krumpe and Debra Van Engelen

NSF-REU Fellowship, Department of Chemistry (2000)
Texas A&M University, College Station, TX
Advisor: Dr. Frank M. Raushel

Publications:

1. De Angelis AA, Howell SC, Opella SJ. Assigning solid-state NMR spectra of aligned proteins using isotropic chemical shifts. J Magn Reson. 2006, 183(2): 329-32.

2. De Angelis AA, Howell SC, Nevzorov AA, Opella SJ. Structure determination of a membrane protein with two trans-membrane helices in aligned phospholipid bicelles by solid-state NMR spectroscopy. J Am Chem Soc. 2006, 128(37): 12256-67.

3. Page RC, Moore JD, Nguyen HB, Sharma M, Chase R, Gao FP, Mobley CK, Sanders CR, Ma L, Sonnichsen FD, Lee S, Howell SC, Opella SJ, Cross TA. Comprehensive evaluation of solution nuclear magnetic resonance spectroscopy sample preparation for helical integral membrane proteins. J Struct Funct Genomics. 2006, 7(1): 51-64.

4. Sinha N, Grant CV, Wu CH, De Angelis AA, Howell SC, Opella SJ. SPINAL modulated decoupling in high field double- and triple-resonance solid-state NMR experiments on stationary samples. J Magn Reson. 2005, 177(2): 197-202.

5. Howell SC, Mesleh MF, Opella SJ. NMR structure determination of a membrane protein with two transmembrane helices in micelles: MerF of the bacterial mercury detoxification system. Biochemistry. 2005, 44(13): 5196-206.

6. De Angelis AA, Nevzorov AA, Park SH, Howell SC, Mrse AA, Opella SJ. High-resolution NMR spectroscopy of membrane proteins in aligned bicelles. J Am Chem Soc. 2004, 126(47): 15340-1.

7.Kim J, Howell S, Huang X, Raushel FM. Structural defects within the carbamate tunnel of carbamoyl phosphate synthetase Biochemistry, 41(42), 12575-81 (2002)

8.Van Engelen D, Howell S, Holmes B. Chemistry 111: Experiments for the general chemistry laboratory UNCA Printing, 2001.